The main setting is Kuken Island, which resides in the middle of a lake.
Ryza is an ordinary girl who lives on the island where Razenboden Village is. She set off a journey outside the island together with her childhood friends Lent and Tao. Along the journey, she met a male alchemist who takes her on as an apprentice. Being an apprentice, it leads her first steps into the world of alchemy. Her friends also begin to face their own dreams.